Tag Archive: swelling


I did some research on the real effects of Tylenol, it might surprise you. What side effects may result from long-term use/high doses of Acetaminophen? What about your liver and kidneys? Mixing with alcohol is even more dangerous yet how many people mix the two everyday?

What can we do? There are many reasons for headaches, diet, stress, misalignment. If we tackle them one at a time we can get closer to the answer instead of masking it with pain pills that lead to further problems. One of our local doctors in Toronto has some great advice on the perils of painkillers, tylenol toxicity and its Alternatives by Zoltan P. Rona, MD, M.Sc. I added some information from his website below that he suggested as alternatives to Tylenol such as Ginger Root, Boswellia, Bromelain, Curcumin and more. See last article.

By , About.com Guide

Updated November 18, 2006

  • The Facts Of Analgesics (Painkillers)
  • Potential For Liver / Kidney Toxicity

    Despite universal acceptance, references have been reported of potential liver and kidney toxicity. These warning reports should alert all users of Tylenol, particularly those who chronically use maximum doses of the drug, to these serious risk factors. Fortunately, patient awareness and routine liver and kidney profile testing will discover any organ abnormality.

    http://arthritis.about.com/od/arthqa/f/tylenol.htm

    The American Association of Poison Control Centers shows the following statistics for reported acetaminophen poisonings in 2001:

    • Total reported exposures: 57,516
    • Reported exposures, under the age of 19: 40,774
    • Unintentional overdoses: 35,705
    • Intentional overdoses: 20,002
    • Total treated for the exposure: 24,934
    • Impact on health from the incident: none, 15,029; minor, 6,223; moderate, 3,138; major, 829; fatal: 120

    Information from: http://headaches.about.com/cs/medicationsusage/a/acet_death.htm

    Dangerous Side Effects

    Serious acetaminophen side effects pose a much greater risk than many consumers realize. In some cases, an individual may experience an acetaminophen side effect and attribute it to some other cause. Sadly, some users even suffer liver failure due to acetaminophen use without their ever knowing.

    Some of the more severe acetaminophen side effects include:

    • Acute liver toxicity
    • Allergic reactions including swelling, difficulty breathing, closing of throat, and more
    • Abdominal pain
    • Nausea
    • Unusual bleeding or bruising
    • Death

    Liver Failure, Death, and Acetaminophen

    Acetaminophen becomes a toxin when large amounts are ingested or under other specific conditions. The U.S. Acute Liver Failure Study Group found that acetaminophen poisoning is the leading cause of liver failure in the nation, accounting for approximately half of all cases. Some of these instances of liver failure occur even when following the dosage recommendations printed on the bottle.

    The following conditions can significantly increase the risk of liver failure and death in acetaminophen users:

    • Heavy alcohol use
    • The simultaneous use of more than one medication containing acetaminophen
    • The simultaneous use of another drug that affects the liver

    If you have decreased liver function, hepatitis, AIDS, malnutrition, kidney disease, anorexia nervosa, or drink alcohol on a regular basis, you should not take acetaminophen without first consulting your doctor. Diabetics should note that acetaminophen may alter blood sugar test results.

    Great information from: http://www.onlinelawyersource.com/acetaminophen/side-effects.html

    An article from a local Doctor here is Toronto with advice on what we can do for an alternative to Tylenol View full article »

    diclofenac/misoprostol – oral, Arthrotec

    SIDE EFFECTS: 

    – diarrhea and upset stomach

    – nausea

    – heartburn

    – gas

    – stomach pain

    – constipation

    – headache

    – tiredness

    – drowsiness

    – dizziness

    **Rarely, diarrhea can become so severe and persistent that it may lead to dehydration

    – severe/persistent diarrhea

    – stomach cramps

    – severe dizziness

    – decreased amount of urine

    – muscle weakness

    ****Tell your doctor immediately if any of these unlikely but serious side effects occur:

    – difficult/painful swallowing

    – swelling of the hands/feet

    – sudden/unexplained weight gain

    – vision changes

    – hearing changes (e.g., ringing in the ears)

    – mental/mood changes (e.g., depression)

    – fast/pounding heartbeat

    – persistent/severe headache

    – fainting 

    – unusual/heavy vaginal bleeding 

    – menstrual problems/irregular periods

    ****Tell your doctor immediately if any of these rare but very serious side effects occur:

    – change in the amount of urine

    – easy bruising/bleeding

    – signs of infection (e.g., fever, persistent sore throat)

    – unexplained stiff neck

    – seizures

    ******This drug may rarely cause serious (possibly fatal) liver disease. If you notice any of the following rare but very serious side effects, stop taking diclofenac/misoprostol and tell your doctor immediately:

    – yellowing eyes/skin

    – dark urine

    – unusual/extreme tiredness

    – severe stomach/abdominal pain

    – persistent nausea/vomiting

    ******A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include:

    – rash

    – itching/swelling (especially of the face/tongue/throat)

    – severe dizziness

    – trouble breathing

    **This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

     

    In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

    In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    PRECAUTIONS: if you are allergic to either of these drugs;

     aspirin or other NSAIDs – ibuprofen, naproxen, celecoxib

    – aspirin-sensitive asthma 

    – recent heart bypass surgery 

    – certain liver problem 

    – kidney disease

    – liver disease

    – stomach/intestine/esophagus problems – bleeding, ulcers, inflammatory bowel disease

    – heart disease

    – high blood pressure, stroke, swelling, edema, fluid retention

    – dehydration

    – blood disorders – anemia)

    – bleeding or clotting problems

    – asthma

    – growths in the nose (nasal polyps)  

    **Before having surgery, tell your doctor or dentist that you are using this medication. This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely.

    *Diclofenac may cause:

    – stomach bleeding. Daily use of alcohol and tobacco may increase your risk for stomach bleeding

    – may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps

    – elderly may be more sensitive to the side effects of this drug, especially stomach/intestinal bleeding and kidney effects.

    – must not be used during pregnancy. It can harm the unborn baby and mother

    *******DRUG INTERACTIONS: This drug should not be used with the following medications because very serious interactions may occur:

    – high doses of aspirin and related drugs – salicylates

    – cidofovir, other NSAIDs – ketorolac

    If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting diclofenac/misoprostol.

    anti-platelet drugs – cilostazol, clopidogrel

    – oral bisphosphonates – alendronate

    – “blood thinners” – enoxaparin, heparin, warfarin

    – corticosteroids – prednisone, cyclosporine, desmopressin, digoxin

    – high blood pressure drugs – ACE inhibitors such as captopril, angiotensin receptor blockers such as loartan, and beta-blockers such as metoprolol, lithium, methotrexate, pemetrexed, probenecid

    – SSRI antidepressants (e.g., fluoxetine, sertraline), “water pills” – diuretics such as furosemide, hydrochlorothiazide, triamterene

    – pain/fever drugs – NSAIDs such as aspirin, celecoxib, ibuprofen. These drugs are similar to this medication, so taking one of these drugs while also taking this medication may increase your risk of side effects

    *******This document does not contain all possible interactions.

    “©2013, WebMD, LLC. All rights reserved”

    My 2 cents:

    I was prescribed these for probably 15 years. I experienced many of the symptoms above yet the doctor never considered them being a side effect from the drugs they were prescribing.  They then went on to give me more drugs  for the symptoms I was having and send me to specialists for this and that, added more diagnoses and more prescriptions to the mix.  Hmmm??? Beside the added expense to our health care. Believe me too, when you involve more doctors you open yourself up to a power struggle of who is right with what diagnoses and then also the ego of the doctor whom is always right. To be honest, it is hard to find doctors who agree with one another.

    Did you read that this is not a complete list of possible side effect? The list just goes on and on. This is because the reports just keep coming in from people so you should keep updated and report your side effects! If you experienced heavy vaginal bleeding they would probably send you to a gynecologist and not even consider your muscle relaxant. Muscle weakness or fatigue you might have a touch of the flu. Abdominal pain, nausea or vomitting probably the same thing or send you for an ultra sound to check your gallbladder. My point here is that one drug can cause so many problems, offer so little cure and it’s side effects or adverse reactions can be masked as disease itself.

    Sources:

    http://www.medicinenet.com/diclofenac_wmisoprostol-oral_tablet/article.htm

     http://naturalpainreliefforfibromyalgia.com/1026

    http://naturalpainreliefforfibromyalgia.com/897

    http://naturalpainreliefforfibromyalgia.com/554